منابع مشابه
Relationship of Soil Ergosterol Concentration and Fungal Biomass
We studied the relationship between amounts of fungi and ergosterol in soil to further evaluate the use of ergosterol as an indicator of soil fungal biomass. Soils from seven sites in central Iowa were analyzed for soil ergosterol content, total fungal hyphal length (living and non-living, using calcofluor as stain), and living fungal hyphal length (using fluorescein diacetate as stain) to: 1) ...
متن کاملMevalonate governs interdependency of ergosterol and siderophore biosyntheses in the fungal pathogen Aspergillus fumigatus.
Aspergillus fumigatus is the most common airborne fungal pathogen for humans. In this mold, iron starvation induces production of the siderophore triacetylfusarinine C (TAFC). Here we demonstrate a link between TAFC and ergosterol biosynthetic pathways, which are both critical for virulence and treatment of fungal infections. Consistent with mevalonate being a limiting prerequisite for TAFC bio...
متن کاملEvaluating the Use of Ergosterol as a Bioindicator for Assessing Fungal Response to Water Quality
This study investigated the in situ production of fungal biomass on presterilized woody substrates submerged in natural estuarine and freshwater bodies enriched with nitrogen and phosphoruscontaining chemical compounds. Results suggest that the membrane-bound sterol ergosterol may hold significant promise as an quantitative indicator of fungal response to water quality. We suggest that realisti...
متن کاملComparison of ATP and ergosterol as indicators of fungal biomass associated with decomposing leaves in streams.
ATP and ergosterol were compared as indicators of fungal biomass associated with leaves decomposing in laboratory microcosms and streams. In all studies, the sporulation rates of the fungi colonizing leaves were also determined to compare patterns of fungal reproductive activity with patterns of mycelial growth. During leaf degradation, ATP concentrations exhibited significant, positive correla...
متن کاملStructural mechanism of ergosterol regulation by fungal sterol transcription factor Upc2.
Transcriptional regulation of ergosterol biosynthesis in fungi is crucial for sterol homeostasis and for resistance to azole drugs. In Saccharomyces cerevisiae, the Upc2 transcription factor activates the expression of related genes in response to sterol depletion by poorly understood mechanisms. We have determined the structure of the C-terminal domain (CTD) of Upc2, which displays a novel α-h...
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ژورنال
عنوان ژورنال: mBio
سال: 2018
ISSN: 2161-2129,2150-7511
DOI: 10.1128/mbio.01755-18